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Crypto at the End of 2025: The Quiet Shift Setting Up 2026
From DeSci and AI to real world infrastructure, the most important crypto stories of 2025 are quietly shaping what comes next
As 2025 comes to an end, crypto has traded the rollercoaster for steady ground. Not feel defeated or euphoric.
It feels… different.
The noise is still there, but the center of gravity has shifted. While most people focused on prices and politics, the real work happened quietly in science, infrastructure, and systems built to last.
Looking toward 2026, that quiet shift might be the most important story crypto has told so far.
Let’s look at what truly moved the needle and what’s still waiting in the wings, unseen.
Crypto Is Maturing (Less Exciting)
This year marked a shift from rebellion to integration.
Regulation became clearer in many regions. Institutions didn’t “kill crypto” they started using it. Builders stopped chasing trends and focused on products that work.
It may not be glamorous,
but this is the foundation that sustains every ecosystem.
The Story Most People Missed: DeSci
While attention stayed on markets, a small corner of crypto started asking a different question:
What if blockchain could fix science?
That’s the idea behind DeSci (Decentralized Science). Instead of closed journals, opaque grants, and slow bureaucracy, DeSci experiments with open funding, transparent research, and token-based collaboration.
Projects to watch:
BIO Protocol — funding biotech research through on-chain coordination
VitaDAO — decentralized longevity research
ResearchHub — open science with crypto incentives
If crypto is going to impact the real world, this is the blueprint.
AI + Crypto: Moving Past the Buzzwords
AI dominated tech this year and crypto followed, beneath the hype, real experiments emerged.
Decentralized AI projects aim to:
Share intelligence, not monopolize it
Reward data, compute, and model contributions
Create open AI markets
Notable projects:
Bittensor — tokenized decentralized intelligence
Fetch.ai — autonomous agents and AI coordination
Ocean Protocol — decentralized data markets
Most will fail.
A few might reshape how AI is built.
When Crypto Finally Touched the Real World
For years, critics asked: Where’s the real-world use?
This year, crypto quietly answered through DePIN.
Decentralized Physical Infrastructure Networks use tokens to coordinate real resources:
Connectivity
Storage
Compute
Examples:
Helium — decentralized wireless networks
Filecoin — decentralized storage infrastructure
Render Network — distributed GPU rendering
Think of crypto not as the internet’s successor, but as its essential new layer. Evolution, not replacement.
Real-World Assets Finally Feel Real
Tokenization of real-world assets (RWA) moved from theory to execution.
We’re now seeing:
Tokenized bonds
On-chain funds
Blockchain-based settlement
Projects pushing RWA forward:
Ondo Finance — tokenized U.S. Treasuries
Centrifuge — real-world asset financing
Chainlink — bridging real-world data on-chain
This is how crypto connects to the global economy.
Stablecoins Did the Real Work (Again)
While narratives came and went, stablecoins quietly powered everything.
They enabled:
Cross-border payments
DeFi liquidity
On-chain settlement at scale
Key players:
USDC
USDT
DAI
Boring? Yes.
Essential? Absolutely.
This year reminded us that:
Hype fades, infrastructure stays
Utility outlasts narratives
The engine room is where the ship is powered.
The era of hype has matured into an era of utility.
Looking Ahead
It’s a mistake to measure crypto’s future in bull runs. The real measure is lasting adoption.
It will be built quietly in science labs, infrastructure networks, AI systems, and financial rails most users will never notice.
And maybe that’s a good thing.
As we move into 2026, I’m curious which part of crypto do you think is most underestimated right now?
The loudest trend, or the quietest one?

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